SCHEMBL29906502

SCHEMBL29906502

C=COCC.O=C(O)COCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.42
GLA P06280 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TSHR P16473 2/20 0.32
CTH P32929 1/20 0.32
CBS P35520 1/20 0.32
THPO P40225 1/20 0.32
FFAR3 O14843 1/20 0.32
EPHX2 P34913 1/20 0.32
THRB P10828 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PAM P19021 2/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL28785631 0.84
Malonic Acid SCHEMBL5779578 0.82 LDHA (0.43) TSHRFFAR3ALDH1A1HCAR2
Acetic Acid SCHEMBL6676468 0.81
Glycine SCHEMBL27759657 0.80 GLRA1 (0.46) TSHRFFAR3ALDH1A1HCAR2
Acrylic Acid SCHEMBL28659504 0.79 LMNA (0.50) TSHRFFAR3ALDH1A1HCAR2
Propene SCHEMBL28007385 0.79 PTGS1 (0.44) PTGS1TSHRCTHCBSTHPO
Maleic Acid SCHEMBL5854822 0.77 HCAR2 (0.52) L3MBTL1TSHRALDH1A1HCAR2
Fumaric Acid SCHEMBL718708 0.77 HCAR2 (0.52) L3MBTL1TSHRALDH1A1HCAR2
Propene SCHEMBL28818285 0.77 PTGS1 (0.40) PTGS1GLAL3MBTL1TSHRCTH
Fumaric Acid SCHEMBL28225492 0.77 HCAR2 (0.52) L3MBTL1TSHRALDH1A1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4171395-A2 COMPRESSIBLE ADJUNCTS WITH DRUG DOSAGE CONTROL FEATURES Cilag GmbH International (CH) 2023-05-03 EP disclosed
EP-4161405-A1 COMPRESSIBLE ADJUNCTS WITH DRUG RELEASE FEATURES Cilag GmbH International (CH) 2023-04-12 EP disclosed
EP-4146089-A2 COMPRESSIBLE ADJUNCTS DIFFERENT BEHAVIORAL ZONES Cilag GmbH International (CH) 2023-03-15 EP disclosed
EP-4146091-A2 COMPRESSIBLE ADJUNCTS WITH FLUID CONTROL FEATURES Cilag GmbH International (CH) 2023-03-15 EP disclosed
EP-4146090-A1 COMPRESSIBLE ADJUNCTS WITH DRUG RELEASE FEATURES Cilag GmbH International (CH) 2023-03-15 EP disclosed
EP-4135597-A1 COMPRESSIBLE ADJUNCTS WITH HEALING-DEPENDENT DEGRADATION PROFILE Cilag GmbH International (CH) 2023-02-22 EP disclosed
EP-4132379-A1 TISSUE THICKNESS COMPENSATING ADJUNCTS HAVING REGIONS OF DIFFERENTIAL EXPANSION Cilag GmbH International (CH) 2023-02-15 EP disclosed
EP-4132381-A1 IMPLANTABLE ADJUNCTS HAVING ADJUSTABLE DEGRADATION PROFILE Cilag GmbH International (CH) 2023-02-15 EP disclosed
EP-4132380-A1 COMPOSITE ADJUNCTS THAT DEGRADE THROUGH MULTIPLE DIFFERENT MECHANISMS Cilag GmbH International (CH) 2023-02-15 EP disclosed
WO-2022208277-A2 COMPRESSIBLE ADJUNCTS WITH DRUG DOSAGE CONTROL FEATURES CILAG GMBH INTERNATIONAL (CH) 2022-10-06 WO disclosed
WO-2022208299-A1 COMPRESSIBLE ADJUNCTS WITH DRUG RELEASE FEATURES CILAG GMBH INTERNATIONAL (CH) 2022-10-06 WO disclosed
WO-2022208292-A1 COMPOSITE ADJUNCTS THAT DEGRADE THROUGH MULTIPLE DIFFERENT MECHANISMS CILAG GMBH INTERNATIONAL (CH) 2022-10-06 WO disclosed
WO-2022208276-A2 COMPRESSIBLE ADJUNCTS DIFFERENT BEHAVIORAL ZONES CILAG GMBH INTERNATIONAL (CH) 2022-10-06 WO disclosed
WO-2022208279-A1 COMPRESSIBLE ADJUNCTS WITH DRUG RELEASE FEATURES CILAG GMBH INTERNATIONAL (CH) 2022-10-06 WO disclosed
WO-2022208297-A1 IMPLANTABLE ADJUNCTS HAVING ADJUSTABLE DEGRADATION PROFILE CILAG GMBH INTERNATIONAL (CH) 2022-10-06 WO disclosed
WO-2022208302-A2 COMPRESSIBLE ADJUNCTS WITH FLUID CONTROL FEATURES CILAG GMBH INTERNATIONAL (CH) 2022-10-06 WO disclosed
WO-2022208296-A1 COMPRESSIBLE ADJUNCTS WITH HEALING-DEPENDENT DEGRADATION PROFILE CILAG GMBH INTERNATIONAL (CH) 2022-10-06 WO disclosed
WO-2022208285-A1 TISSUE THICKNESS COMPENSATING ADJUNCTS HAVING REGIONS OF DIFFERENTIAL EXPANSION CILAG GMBH INTERNATIONAL (CH) 2022-10-06 WO disclosed