Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28785631 | 0.92 | — | — | |
| Methacrylic Acid SCHEMBL5624304 | 0.88 | THRB (0.36) | — | |
| SCHEMBL8733236 | 0.87 | ALDH1A1 (0.55) | — | |
| Acrylic Acid SCHEMBL28659504 | 0.87 | LMNA (0.50) | — | |
| Fumaric Acid SCHEMBL718708 | 0.85 | HCAR2 (0.52) | — | |
| Maleic Acid SCHEMBL5854822 | 0.85 | HCAR2 (0.52) | — | |
| Malonic Acid SCHEMBL5779578 | 0.85 | LDHA (0.43) | — | |
| Fumaric Acid SCHEMBL28225492 | 0.85 | HCAR2 (0.52) | — | |
| Urea SCHEMBL27407445 | 0.84 | — | — | |
| SCHEMBL4948994 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018728-A | PIGMENTARY MATERIALS, HOT MELT ADHESIVES, PLASTICIZER AND SOLVENT | JOHNSON MATTHEY & CO., LIMITED (EN) | 1977-04-19 | — | — | US | claimed |
| CN-113136196-A | Fracturing fluid composition, preparation method of fracturing fluid, fracturing fluid and fracturing method | 中国石油天然气股份有限公司 | 2021-07-20 | — | — | CN | disclosed |
| EP-1220851-B1 | CARBON DIOXIDE-PHILIC COMPOUNDS AND METHODS OF SYNTHESIS THEREOF | UNIV PITTSBURGH (US) | 2004-08-18 | — | — | EP | disclosed |
| US-20040158013-A1 | Carbon dioxide-philic compounds and methods of synthesis thereof | BECKMAN ERIC J (US) | 2004-08-12 | — | — | US | disclosed |
| US-6686438-B1 | REACTING THE CO2-PHOBIC COMPOUND WITH A CO2-PHILIC COMPOUND, WHEREIN THE CO2-PHILIC COMPOUND IS A POLYETHER SUBSTITUTED WITH AT LEAST ONE SIDE GROUP INCORPORATING A LEWIS BASE | UNIVERSITY OF PITTSBURGH | 2004-02-03 | — | — | US | disclosed |
| EP-1220851-A4 | CARBON DIOXIDE-PHILIC COMPOUNDS AND METHODS OF SYNTHESIS THEREOF | UNIV PITTSBURGH (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-1220851-A1 | CARBON DIOXIDE-PHILIC COMPOUNDS AND METHODS OF SYNTHESIS THEREOF | UNIVERSITY OF PITTSBURGH (US) | 2002-07-10 | — | — | EP | disclosed |
| WO-2001021616-A1 | CARBON DIOXIDE-PHILIC COMPOUNDS AND METHODS OF SYNTHESIS THEREOF | UNIVERSITY OF PITTSBURGH (US) | 2001-03-29 | — | — | WO | disclosed |
| US-4208488-A | POLYESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-06-17 | — | — | US | disclosed |