Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 5/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340477 | 0.88 | KMT2A (0.45) | CDK1CCNB1KMT2ATLR8CCNA2 | |
| SCHEMBL8446516 | 0.81 | NPC1 (0.54) | KMT2ANPC1ALDH1A1MAPK1RAB9A | |
| SCHEMBL2990823 | 0.81 | CDK1 (0.46) | CDK1CCNB1KMT2ATLR8CCNA2 | |
| SCHEMBL17581241 | 0.80 | KMT2A (0.44) | KMT2ATSHRNPC1ALDH1A1MAPK1 | |
| SCHEMBL4564977 | 0.80 | NUDT1 (0.58) | CDK1CCNB1KMT2ATLR8CCNA2 | |
| SCHEMBL17589003 | 0.77 | HTR7 (0.46) | KMT2A | |
| SCHEMBL10398846 | 0.76 | CDK1 (0.43) | CDK1CCNB1KMT2ATLR8CCNA2 | |
| SCHEMBL2987423 | 0.75 | ALDH1A1 (0.46) | CDK1CCNB1KMT2ATLR8CCNA2 | |
| SCHEMBL8505540 | 0.74 | SMPD1 (0.37) | TLR8 | |
| SCHEMBL7638429 | 0.73 | TLR8 (0.56) | KMT2ATLR8TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378089-B1 | Method for the preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AG (DE) | 1994-06-29 | — | — | EP | disclosed |
| US-5011927-A | Preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |
| EP-0378089-A1 | Method for the preparation of 2-amino-4-fluoropyrimidine derivatives | BASF Aktiengesellschaft (DE) | 1990-07-18 | — | — | EP | disclosed |