Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 2/20 | 0.32 |
| ▸ | CRY1 | Q16526 | 2/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909810 | 0.82 | TNIK (0.33) | PER2CRY1CRY2 | |
| SCHEMBL23601998 | 0.82 | TNIK (0.33) | PER2CRY1CRY2 | |
| SCHEMBL23601256 | 0.80 | PER2 (0.31) | PER2CRY1CRY2 | |
| SCHEMBL29909064 | 0.79 | HTR6 (0.32) | PER2CRY1CRY2 | |
| SCHEMBL23577671 | 0.79 | HTR6 (0.32) | PER2CRY1CRY2 | |
| SCHEMBL29909187 | 0.76 | — | — | |
| SCHEMBL23601258 | 0.75 | — | — | |
| SCHEMBL29909773 | 0.75 | — | — | |
| SCHEMBL29909653 | 0.75 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL29909097 | 0.72 | CRY1 (0.30) | CRY1CRY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12054490-B2 | Diacylglycerol kinase modulating compounds | GILEAD SCIENCES, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12054490-B2 | Diacylglycerol kinase modulating compounds | DGKG, DGKB, DGKK | PER2 3692/4885CRY1 4814/4885CRY2 4680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.