SCHEMBL29909810

SCHEMBL29909810

CC(C)(O)C#Cc1cc(F)cc(N(c2nc3nncn3c3ccc(F)cc23)C2CC2)c1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TNIK Q9UKE5 2/20 0.33
PER2 O15055 2/20 0.31
CRY1 Q16526 2/20 0.31
CRY2 Q49AN0 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23601998 1.00 TNIK (0.33) TNIKPER2CRY1CRY2
SCHEMBL23601258 0.85
SCHEMBL29909040 0.82 PER2 (0.32) PER2CRY1CRY2
SCHEMBL23601256 0.81 PER2 (0.31) PER2CRY1CRY2
SCHEMBL29909064 0.80 HTR6 (0.32) PER2CRY1CRY2
SCHEMBL23577671 0.80 HTR6 (0.32) PER2CRY1CRY2
SCHEMBL29909404 0.79 MAPT (0.30)
SCHEMBL23577331 0.79 MAPT (0.30)
SCHEMBL23576975 0.77
SCHEMBL29909855 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4081305-B1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS CARNA BIOSCIENCES INC (JP) 2024-09-18 EP disclosed
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed