⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL445950 | 1.00 | — | — | |
| SCHEMBL22896965 | 0.83 | GRM5 (0.35) | — | |
| SCHEMBL23887607 | 0.81 | SYK (0.42) | — | |
| SCHEMBL17601584 | 0.78 | LMNA (0.43) | — | |
| SCHEMBL1782191 | 0.77 | — | — | |
| SCHEMBL31205727 | 0.77 | — | — | |
| SCHEMBL1774897 | 0.77 | GAA (0.42) | — | |
| SCHEMBL1519145 | 0.77 | TLR8 (0.42) | — | |
| SCHEMBL21550282 | 0.75 | ESR1 (0.35) | — | |
| SCHEMBL20685774 | 0.75 | MAPK14 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |