⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1782191 | 1.00 | — | — | |
| SCHEMBL23887607 | 0.81 | SYK (0.42) | — | |
| SCHEMBL27764814 | 0.78 | GABRA1 (0.38) | — | |
| SCHEMBL445950 | 0.77 | — | — | |
| SCHEMBL29909710 | 0.77 | — | — | |
| Salicyladehyde SCHEMBL29001184 | 0.77 | TRIM24 (0.49) | — | |
| SCHEMBL11256791 | 0.74 | — | — | |
| SCHEMBL12998775 | 0.74 | KDM4E (0.52) | — | |
| SCHEMBL22896965 | 0.74 | GRM5 (0.35) | — | |
| SCHEMBL17601584 | 0.74 | LMNA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709723-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233544-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |