SCHEMBL29910050

SCHEMBL29910050

NC1=Nc2nc[nH]c2C(=O)C1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 2/20 0.33
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
ATIC P31939 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30838807 0.98 GDA (0.32) GDA
SCHEMBL1338837 0.68 ALDH1A1 (0.31) ALDH1A1POLBRXFP1ATIC
SCHEMBL9049462 0.65 ALDH1A1 (0.32) GDAALDH1A1POLBRXFP1ATIC
SCHEMBL905427 0.64 PNP (0.31) GDAALDH1A1
SCHEMBL4748766 0.64 ALDH1A1 (0.31) ALDH1A1POLBRXFP1ATIC
SCHEMBL17425088 0.63 ALDH1A1 (0.30) ALDH1A1POLBRXFP1ATIC
SCHEMBL15414257 0.62 GDA (0.42) GDAALDH1A1POLBRXFP1ATIC
SCHEMBL8011952 0.58 GDA (0.38) GDAALDH1A1POLBRXFP1ATIC
SCHEMBL4455591 0.56
SCHEMBL10612254 0.55 ALDH1A1 (0.31) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250076302-A1 DETECTING THE PRESENCE OF URINARY STONE DISEASE USING A PLURALITY OF URINARY METABOLITES THE CLEVELAND CLINIC FOUNDATION 2025-03-06 US disclosed
US-20250052717-A1 METHODS AND DEVICES FOR SEQUENCING NUCLEIC ACIDS IN SMALLER BATCHES QIAGEN SCIENCES, LLC 2025-02-13 US disclosed
EP-4367235-A1 COMPOSITIONS AND METHODS FOR DETECTING GENETIC FEATURES Singular Genomics Systems, Inc. (US) 2024-05-15 EP disclosed
US-11940413-B2 Methods and devices for sequencing nucleic acids in smaller batches IsoPlexis Corporation (US) 2024-03-26 US disclosed
US-20240076731-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES QIAGEN SCIENCES, LLC 2024-03-07 US disclosed
US-20240060128-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES QIAGEN WALTHAM, INC. 2024-02-22 US disclosed
EP-4271839-A1 PHASE PROTECTIVE REAGENT FLOW ORDERING Singular Genomics Systems, Inc. (US) 2023-11-08 EP disclosed
WO-2022197942-A9 PHASE PROTECTIVE REAGENT FLOW ORDERING Singular Genomics Systems, Inc. (US) 2023-02-23 WO disclosed
WO-2023283090-A1 COMPOSITIONS AND METHODS FOR DETECTING GENETIC FEATURES Singular Genomics Systems, Inc. (US) 2023-01-12 WO disclosed
WO-2022272150-A2 LINKED TRANSCRIPT SEQUENCING Singular Genomics Systems, Inc. (US) 2022-12-29 WO disclosed
WO-2022197942-A1 PHASE PROTECTIVE REAGENT FLOW ORDERING Singular Genomics Systems, Inc. (US) 2022-09-22 WO disclosed
EP-4055023-A1 SILICON CONTAINING DETECTABLE COMPOUNDS AND USES THEREOF Singular Genomics Systems, Inc. (US) 2022-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240076731-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES NT5C2, NOP2, NT5C3B GDA 92/4885ALDH1A1 4837/4885POLB 44/4885
US-20240060128-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES NT5C2, NOP2, NT5C3B GDA 92/4885ALDH1A1 4837/4885POLB 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.