Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ATIC | P31939 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 2/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857549 | 0.69 | ALDH1A1 (0.31) | ALDH1A1POLBRXFP1PNPABL1 | |
| SCHEMBL7011289 | 0.60 | ATIC (0.36) | ALDH1A1POLBRXFP1ATIC | |
| SCHEMBL662729 | 0.60 | GDA (0.40) | ALDH1A1POLBRXFP1ATIC | |
| SCHEMBL1072291 | 0.58 | IDO1 (0.36) | — | |
| SCHEMBL4455591 | 0.57 | — | — | |
| SCHEMBL5165263 | 0.56 | ALDH1A1 (0.44) | ALDH1A1POLBRXFP1ATIC | |
| SCHEMBL13735762 | 0.56 | ALDH1A1 (0.65) | ALDH1A1POLBRXFP1ATIC | |
| SCHEMBL8011952 | 0.55 | GDA (0.38) | ALDH1A1POLBRXFP1ATIC | |
| SCHEMBL14793621 | 0.54 | HPGD (0.38) | ALDH1A1POLB | |
| SCHEMBL8009805 | 0.54 | ATIC (0.34) | ALDH1A1POLBRXFP1ATICPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744236-B2 | Photolabile compounds | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-08-29 | — | — | US | disclosed |
| US-9688708-B2 | Photolabile compounds | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-06-27 | — | — | US | disclosed |
| US-20160176907-A1 | Photolabile Compounds | UNIVERSIDAD DE BUENOS AIRES (AR) | 2016-06-23 | — | — | US | disclosed |
| US-9273032-B2 | Photolabile compounds | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-03-01 | — | — | US | disclosed |
| US-20150032045-A1 | PHOTOLABILE COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-01-29 | — | — | US | disclosed |
| WO-2013096836-A1 | PHOTOLABILE COMPOUNDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2013-06-27 | — | — | WO | disclosed |
| US-20120220922-A1 | PHOTOLABILE COMPOUNDS | UNIVERSIDAD DE BUENOS AIRES (AR) | 2012-08-30 | — | — | US | disclosed |
| US-20120116287-A1 | PHOTOLABILE COMPOUNDS | UNIVERSIDAD DE BUENOS AIRES (AR) | 2012-05-10 | — | — | US | disclosed |
| EP-2445917-A1 | PHOTOLABILE COMPOUNDS | The Trustees of Columbia University in the City of New York (US) | 2012-05-02 | — | — | EP | disclosed |
| US-8063216-B2 | have a photoreleasable ligand, which can be biologically active, and which is photoreleased from the compound upon exposure to light | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2011-11-22 | — | — | US | disclosed |
| WO-2010151879-A1 | PHOTOLABILE COMPOUNDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-12-29 | — | — | WO | disclosed |
| US-20080176940-A1 | Photolabile Compounds | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-07-24 | — | — | US | disclosed |
| WO-2005065192-A2 | PHOTOLABILE COMPOUNDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2005-07-21 | — | — | WO | disclosed |
| EP-0845476-B1 | Synthetic catalytic oligonucleotides | EUROPAEISCHES LAB FUER (DE) | 2001-03-14 | — | — | EP | disclosed |
| EP-1061085-A2 | Synthetic catalytic oligonucleotides | EUROPÄISCHES LABORATORIUM FÜR MOLEKULARBIOLOGIE (EMBL) (DE) | 2000-12-20 | — | — | EP | disclosed |
| EP-0519463-B1 | Synthetic, catalytic oligonucleotides | EUROP LAB MOLEKULARBIOLOG (DE) | 1998-10-21 | — | — | EP | disclosed |
| EP-0845476-A2 | Synthetic catalytic oligonucleotides | EUROPÄISCHES LABORATORIUM FÜR MOLEKULARBIOLOGIE (EMBL) (DE) | 1998-06-03 | — | — | EP | disclosed |
| US-5334711-A | To cleave a nucleic acid target sequence; double-stranded; increased stability; reduced protein interaction; viricides; AIDS | EUROPAISCHES LABORATORIUM FUR MOLEKULARBIOLOGIE (EMBL) (DE) | 1994-08-02 | — | — | US | disclosed |
| EP-0519463-A1 | Synthetic, catalytic oligonucleotides | EUROPÄISCHES LABORATORIUM FÜR MOLEKULARBIOLOGIE (EMBL) (DE) | 1992-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150032045-A1 | PHOTOLABILE COMPOUNDS | VIP, EPCAM, L1CAM | ALDH1A1 94/4885POLB 1554/4885RXFP1 2315/4885 |
| US-20160176907-A1 | Photolabile Compounds | HMBS, CASP3, CRY1 | ALDH1A1 94/4885POLB 1005/4885RXFP1 2333/4885 |
| US-20120220922-A1 | PHOTOLABILE COMPOUNDS | VIP, EPCAM, L1CAM | ALDH1A1 94/4885POLB 1554/4885RXFP1 2315/4885 |
| US-20120116287-A1 | PHOTOLABILE COMPOUNDS | HMBS, CASP3, CRY1 | ALDH1A1 94/4885POLB 1005/4885RXFP1 2333/4885 |
| US-20080176940-A1 | Photolabile Compounds | HMBS, CASP3, CRY1 | ALDH1A1 94/4885POLB 1005/4885RXFP1 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.