Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.59 |
| ▸ | MMP2 | P08253 | 11/20 | 0.59 |
| ▸ | MMP9 | P14780 | 11/20 | 0.59 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.56 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.56 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19858953 | 1.00 | MMP1 (0.59) | MMP1MMP2MMP9LTB4RTRPM2 | |
| SCHEMBL14801853 | 1.00 | MMP1 (0.59) | MMP1MMP2MMP9LTB4RTRPM2 | |
| SCHEMBL14801687 | 0.92 | MMP1 (0.61) | MMP1MMP2MMP9LTB4RTRPM2 | |
| SCHEMBL14801681 | 0.92 | MMP1 (0.61) | MMP1MMP2MMP9LTB4RTRPM2 | |
| SCHEMBL14801990 | 0.88 | MMP1 (0.65) | MMP1MMP2MMP9MAOAMAOB | |
| SCHEMBL23781993 | 0.86 | MMP1 (0.63) | MMP1MMP2MMP9MAOAMAOB | |
| SCHEMBL14801863 | 0.86 | MMP1 (0.63) | MMP1MMP2MMP9MAOAMAOB | |
| SCHEMBL14801934 | 0.82 | NFKB1 (0.53) | MMP1MMP2MMP9LTB4RTRPM2 | |
| SCHEMBL8213614 | 0.82 | NFKB1 (0.53) | MMP1MMP2MMP9LTB4RTRPM2 | |
| SCHEMBL29401064 | 0.81 | TRPM2 (0.81) | MMP1MMP2MMP9LTB4RTRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4114349-A1 | COMPOSITION OR OAT EXTRACT COMPRISING AVENANTHRAMIDE AND BETA-GLUCAN | Symrise AG (DE) | 2023-01-11 | — | — | EP | disclosed |
| EP-4114348-A1 | COMPOSITION COMPRISING AN AVENTHRAMIDE OR AN ANALOGUE THEREOF WITH IMPROVED STABILITY | Symrise AG (DE) | 2023-01-11 | — | — | EP | disclosed |
| EP-4114354-A1 | AVENANTHRAMIDE COMPOSITIONS WITH IMPROVED SOLUBILITY COMPRISING 4-HYDROXYPHENONE | Symrise AG (DE) | 2023-01-11 | — | — | EP | disclosed |
| CN-115279333-A | Composition or oat extract comprising avenanthramide and beta-glucan | 西姆莱斯股份公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115243669-A | Avenanthramide compositions with enhanced solubility comprising 4-hydroxybenzophenones | 西姆莱斯股份公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115243670-A | Cosmetic or pharmaceutical use of avenanthramide L | 西姆莱斯股份公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115243664-A | Compositions comprising avenanthramides for increasing skin permeability | 西姆莱斯股份公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115209864-A | Compositions comprising avenanthramides or analogs thereof having improved stability | 西姆莱斯股份公司 | 2022-10-18 | — | — | CN | disclosed |