Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | GUSB | P08236 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14801934 | 1.00 | NFKB1 (0.53) | NFKB1CA1CA2CA4BCHE | |
| SCHEMBL14801687 | 0.87 | MMP1 (0.61) | BCHETRPA1TRPM8LTB4RMAPT | |
| SCHEMBL14801681 | 0.87 | MMP1 (0.61) | BCHETRPA1TRPM8LTB4RMAPT | |
| SCHEMBL2779546 | 0.84 | TRPA1 (0.72) | NFKB1CA1CA2CA4BCHE | |
| SCHEMBL2779548 | 0.84 | TRPA1 (0.72) | NFKB1CA1CA2CA4BCHE | |
| SCHEMBL29913624 | 0.82 | MMP1 (0.59) | TRPA1TRPM8LTB4RMAPTMMP1 | |
| SCHEMBL14801853 | 0.82 | MMP1 (0.59) | TRPA1TRPM8LTB4RMAPTMMP1 | |
| SCHEMBL19858953 | 0.82 | MMP1 (0.59) | TRPA1TRPM8LTB4RMAPTMMP1 | |
| SCHEMBL14801947 | 0.81 | TRPM8 (0.58) | NFKB1BCHETRPA1TRPM8NFE2L2 | |
| SCHEMBL14801990 | 0.81 | MMP1 (0.65) | MMP1MMP2MMP9MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10280441-B2 | Host cells and methods for producing cinnamoyl anthranilate and analogs thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-05-07 | — | — | US | disclosed |
| US-20130078683-A1 | Host Cells and Methods for Producing Cinnamoyl Anthranilate and Analogs Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-28 | — | — | US | disclosed |
| US-6117365-A | N-(3,4-DIHYDROXYBENZYL)-3,5-DIMETHOXY-4-HYDROXY-E-CINNAMIDE, FOR EXAMPLE; USE AS ANTIOXIDANTS OR AS FREE-RADICAL SCAVENGERS, IN PARTICULAR IN THE COSMETIC OR DERMATOLOGICAL FIELDS, AND IN FOODS | HAARMANN & REIMER GMBH (DE) | 2000-09-12 | — | — | US | disclosed |