SCHEMBL2991364

SCHEMBL2991364

CCc1cc(C)cc(CC)c1C1C(=O)CC2(CCOCC2)CC1=O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21361213 0.84 CYP11B2 (0.32) KMT2A
SCHEMBL1038175 0.74 ALDH1A1 (0.31)
SCHEMBL1830730 0.74
SCHEMBL11326010 0.74 SMN1; SMN2 (0.31) ATM
SCHEMBL417562 0.73 BACE1 (0.33) MEN1KMT2ANPSR1HSD17B10
SCHEMBL560005 0.72 DAO (0.30)
SCHEMBL13263829 0.72 CYP11B2 (0.32)
SCHEMBL2684808 0.71 GLA (0.33) KMT2A
SCHEMBL2993701 0.71 SMN1; SMN2 (0.33) HSD17B10
Pinoxaden Dione SCHEMBL64757 0.71 TSHR (0.39) MEN1KMT2AATMNPSR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8084649-B2 Herbicides SYNGENTA CROP PROTECTION, INC. (US) 2011-12-27 US disclosed
US-20100173774-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION, INC. (US) 2010-07-08 US disclosed
EP-2121584-A2 NOVEL HERBICIDES Syngeta Participations AG (CH) 2009-11-25 EP disclosed
WO-2008110308-A2 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2008-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100173774-A1 NOVEL HERBICIDES DDT, HDHD5, HPD MEN1 4755/4885KMT2A 1123/4885ATM 3868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.