Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920510 | 1.00 | CA2 (0.32) | CA2NR3C1NR3C2LTB4RLTB4R2 | |
| SCHEMBL29920659 | 1.00 | CA2 (0.32) | CA2NR3C1NR3C2LTB4RLTB4R2 | |
| SCHEMBL29920646 | 0.84 | CA2 (0.43) | CA2NR3C1NR3C2LTB4RLTB4R2 | |
| SCHEMBL29920642 | 0.84 | CA2 (0.43) | CA2NR3C1NR3C2LTB4RLTB4R2 | |
| SCHEMBL29920552 | 0.77 | CA2 (0.42) | CA2LTB4RLTB4R2 | |
| SCHEMBL29920570 | 0.77 | CA2 (0.42) | CA2LTB4RLTB4R2 | |
| SCHEMBL29920554 | 0.70 | LTB4R (0.44) | CA2NR3C1NR3C2LTB4RLTB4R2 | |
| SCHEMBL29920403 | 0.70 | LTB4R (0.44) | CA2NR3C1NR3C2LTB4RLTB4R2 | |
| SCHEMBL29920674 | 0.66 | TRPV1 (0.34) | — | |
| SCHEMBL30850194 | 0.61 | CHRNB2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |