Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920290 | 1.00 | CA2 (0.38) | CA2KCNE1KCNQ1LTB4RLTB4R2 | |
| SCHEMBL29920403 | 0.73 | LTB4R (0.44) | CA2LTB4RLTB4R2NR3C1NR3C2 | |
| SCHEMBL29920554 | 0.73 | LTB4R (0.44) | CA2LTB4RLTB4R2NR3C1NR3C2 | |
| SCHEMBL29920312 | 0.72 | TRPV1 (0.43) | KCNE1KCNQ1TRPV1 | |
| SCHEMBL29920334 | 0.72 | TRPV1 (0.43) | KCNE1KCNQ1TRPV1 | |
| SCHEMBL25523284 | 0.71 | HTR2B (0.39) | HTR1AHTR2BSIGMAR1SLC6A2HTR2C | |
| SCHEMBL25859350 | 0.69 | HTR2A (0.40) | HTR2BSLC6A2HTR2C | |
| SCHEMBL29920502 | 0.67 | CA2 (0.43) | CA2KCNE1KCNQ1LTB4RLTB4R2 | |
| SCHEMBL29920313 | 0.67 | PSEN1 (0.35) | CA2KCNE1KCNQ1LTB4RLTB4R2 | |
| SCHEMBL29920566 | 0.67 | CA2 (0.43) | CA2KCNE1KCNQ1LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |