SCHEMBL29920883

SCHEMBL29920883

CNC(=O)c1ccc(Oc2ccc(C(C)(C)C)cc2)c(F)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.54
TSHR P16473 1/20 0.54
HTT P42858 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
ALDH1A1 P00352 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
MMP13 P45452 1/20 0.49
EPHX2 P34913 2/20 0.47
NR1H4 Q96RI1 2/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.45
PLK1 P53350 1/20 0.45
ESRRG P62508 1/20 0.44
TRPV1 Q8NER1 1/20 0.44
GAA P10253 1/20 0.43
KCNQ3 O43525 1/20 0.43
KCNQ2 O43526 1/20 0.43
KCNE1 P15382 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21657035 1.00 HPGD (0.54) HPGDTSHRHTTSMN1; SMN2SLC6A2
SCHEMBL21628876 0.90 HDAC1 (0.58) HPGDALDH1A1NPSR1MAPTKDM4E
SCHEMBL21628694 0.90 MAPT (0.54) HPGDTSHRHTTSMN1; SMN2SLC6A2
SCHEMBL21628487 0.88 SLC6A2 (0.49) HPGDTSHRHTTSMN1; SMN2SLC6A2
SCHEMBL21628492 0.87 HPGD (0.51) HPGDTSHRHTTSMN1; SMN2SLC6A2
SCHEMBL21628649 0.87 HPGD (0.51) HPGDTSHRHTTSMN1; SMN2SLC6A2
SCHEMBL21628412 0.85 ALDH1A1 (0.66) HPGDHTTALDH1A1NPSR1MAPT
SCHEMBL21628504 0.85 SLC6A2 (0.49) HPGDTSHRHTTSMN1; SMN2SLC6A2
SCHEMBL19357374 0.85 RAB9A (0.56) HPGDHTTALDH1A1NPSR1EPHX2
SCHEMBL21656765 0.85 MMP13 (0.65) HPGDTSHRHTTSMN1; SMN2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220348535-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2022-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220348535-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK HPGD 2579/4885TSHR 3747/4885HTT 550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.