SCHEMBL21628487

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628693	0.91	NPC1 (0.47)	NPC1RAB9APOLBCYP2C9MAPT
	SCHEMBL21657035	0.88	HPGD (0.54)	SLC6A2SLC6A4HPGDTSHRHTT
	SCHEMBL29920883	0.88	HPGD (0.54)	SLC6A2SLC6A4HPGDTSHRHTT
	SCHEMBL21628854	0.87	ALDH1A1 (0.52)	HPGDNPC1RAB9APOLBCYP2C9
	SCHEMBL21628475	0.86	RAB9A (0.63)	HTTNPC1RAB9APOLBCYP2C9
	SCHEMBL21628416	0.85	PARP10 (0.50)	SLC6A2SLC6A4NPC1RAB9APOLB
	SCHEMBL21628694	0.85	MAPT (0.54)	SLC6A2SLC6A4HPGDTSHRHTT
	SCHEMBL21628640	0.85	HPGD (0.69)	HPGDTSHRHTTSMN1; SMN2NPC1
	SCHEMBL21628755	0.83	SLC6A2 (0.51)	SLC6A2SLC6A4HPGDSMN1; SMN2NPC1
	SCHEMBL21628492	0.83	HPGD (0.51)	SLC6A2SLC6A4HPGDTSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.