Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708356 | 0.83 | PDE2A (0.39) | PDE2APDCD1LG2CD274 | |
| SCHEMBL6351805 | 0.79 | L3MBTL1 (0.30) | — | |
| SCHEMBL21130064 | 0.79 | CRHBP (0.30) | — | |
| SCHEMBL5748896 | 0.79 | LMNA (0.38) | PDCD1LG2CD274 | |
| SCHEMBL3704304 | 0.75 | P2RX7 (0.35) | PDCD1LG2CD274 | |
| SCHEMBL22571303 | 0.75 | PDCD1LG2 (0.32) | PDCD1LG2CD274 | |
| SCHEMBL8550099 | 0.74 | PDE2A (0.38) | PDE2APDCD1LG2CD274 | |
| SCHEMBL22638204 | 0.72 | TDP1 (0.39) | PDE2A | |
| SCHEMBL22632626 | 0.72 | TDP1 (0.39) | PDE2A | |
| SCHEMBL4706546 | 0.72 | APLNR (0.31) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188735-A1 | HETEROCYCLIC COMPOUNDS AS HPK1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |