Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL521102 | 0.75 | KDM4E (0.55) | BRPF1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3872734 | 0.73 | GPR3 (0.44) | BRPF1TTRMEN1KMT2ATLR9 | |
| SCHEMBL2358278 | 0.72 | NQO2 (0.61) | BRPF1TTRMEN1KMT2ATLR9 | |
| Hydrochloric Acid SCHEMBL19896390 | 0.72 | MEN1 (0.42) | BRPF1TTRMEN1KMT2ATLR9 | |
| SCHEMBL297992 | 0.72 | KDM4E (0.60) | BRPF1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL27240229 | 0.71 | ALDH1A1 (0.47) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL27240400 | 0.71 | CYP19A1 (0.41) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29922141 | 0.71 | DDB1 (0.39) | BRPF1TTRMEN1KMT2ATLR9 | |
| SCHEMBL6330237 | 0.71 | L3MBTL1 (0.71) | MEN1KMT2ATLR9L3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL16633753 | 0.70 | KDM4E (0.63) | BRPF1MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188735-A1 | HETEROCYCLIC COMPOUNDS AS HPK1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |