Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.39 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28359050 | 1.00 | SYK (0.46) | SYKEGFRGSK3BLRRK2AVPR2 | |
| SCHEMBL15091096 | 0.85 | SYK (0.56) | SYKNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL15091106 | 0.83 | LMNA (0.41) | SYKLRRK2JAK2TYK2TNIK | |
| SCHEMBL29922937 | 0.82 | SYK (0.46) | SYKRAB9AKDM4EALDH1A1 | |
| SCHEMBL29922724 | 0.82 | SYK (0.46) | SYKGSK3BCCNB2CCNE2CDK1 | |
| SCHEMBL28359017 | 0.82 | SYK (0.46) | SYKGSK3BCCNB2CCNE2CDK1 | |
| SCHEMBL28359009 | 0.82 | SYK (0.46) | SYKRAB9AKDM4EALDH1A1 | |
| SCHEMBL28362794 | 0.81 | SYK (0.45) | SYKLRRK2RAB9APTGS2KDM4E | |
| SCHEMBL29922643 | 0.80 | ALDH1A1 (0.47) | SYKNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL28359257 | 0.80 | ALDH1A1 (0.47) | SYKNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818641-B | Pyridazine-3-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-10-14 | — | — | CN | disclosed |