Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915691 | 1.00 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2L3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL29923655 | 0.84 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EKMT2A | |
| SCHEMBL24916324 | 0.84 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EKMT2A | |
| SCHEMBL24916059 | 0.82 | POLB (0.41) | ALDH1A1SMN1; SMN2L3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL29923420 | 0.81 | GABRA1 (0.45) | ALDH1A1SMN1; SMN2CYP4F2CYP4A11KDM4E | |
| SCHEMBL22750311 | 0.81 | GABRA1 (0.45) | ALDH1A1SMN1; SMN2CYP4F2CYP4A11KDM4E | |
| SCHEMBL3928069 | 0.74 | CA12 (0.43) | ALDH1A1SMN1; SMN2L3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL6586612 | 0.73 | CCR6 (0.53) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EKMT2A | |
| SCHEMBL22766603 | 0.72 | GABRA1 (0.47) | ALDH1A1SMN1; SMN2L3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL24916110 | 0.71 | CA12 (0.47) | ALDH1A1CYP4F2CYP4A11KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |