Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.51 |
| ▸ | PARP1 | P09874 | 6/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.42 |
| ▸ | WDR5 | P61964 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22990503 | 0.86 | PARP10 (0.46) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL4820188 | 0.84 | LMNA (0.47) | LMNAL3MBTL1WDR5HTR1AHTR2C | |
| SCHEMBL29923517 | 0.81 | TYMP (0.46) | PARP10PARP1F7F3LMNA | |
| SCHEMBL8162850 | 0.74 | PARP10 (0.63) | PARP10PARP1F7F3LMNA | |
| SCHEMBL29698238 | 0.74 | WDR5 (0.50) | LMNAL3MBTL1WDR5 | |
| SCHEMBL22981926 | 0.74 | WDR5 (0.50) | LMNAL3MBTL1WDR5 | |
| SCHEMBL24886164 | 0.74 | WDR5 (0.52) | LMNAL3MBTL1WDR5 | |
| SCHEMBL8255407 | 0.72 | PARP10 (0.59) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL31270697 | 0.72 | LMNA (0.74) | LMNAL3MBTL1HTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL31315569 | 0.71 | MET (0.42) | LMNAL3MBTL1WDR5HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999716-B2 | WDR5 inhibitors and modulators | VANDERBILT UNIVERSITY (US) | 2024-06-04 | — | — | US | disclosed |
| US-20230012362-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-12 | — | — | US | disclosed |
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230012362-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR77 | PARP10 501/4885PARP1 1588/4885F7 4863/4885 |
| US-11999716-B2 | WDR5 inhibitors and modulators | WDR5, WDR1, WDR3 | PARP10 555/4885PARP1 1697/4885F7 4870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.