Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.49 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915560 | 0.80 | PIK3CA (0.50) | HPGDSPIK3CAMTORKDM4EALDH1A1 | |
| SCHEMBL29923911 | 0.75 | NFKBIA (0.49) | KDM4EALDH1A1SMN1; SMN2NFKBIAMAPT | |
| SCHEMBL2015530 | 0.75 | KDM4E (0.49) | KDM4EALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL29923203 | 0.74 | PSMD14 (0.42) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29923773 | 0.69 | KMT2A (0.47) | HPGDSKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL13373465 | 0.68 | HPGD (0.61) | PIK3CAMTORALDH1A1NPC1RAB9A | |
| SCHEMBL12521829 | 0.68 | KCNMA1 (0.67) | KDM4EALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL28529190 | 0.65 | NFKBIA (0.50) | NPC1RAB9ALMNANFKBIAMAPT | |
| SCHEMBL17159814 | 0.65 | PIM1 (0.69) | HPGDSPIK3CAMTORKDM4ENPC1 | |
| SCHEMBL13373471 | 0.65 | RAB9A (0.61) | HPGDSKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |