Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 6/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16156637 | 1.00 | LPL (0.41) | LPLLIPGCCNCCDK8IDO1 | |
| SCHEMBL17144060 | 0.88 | LPL (0.41) | LPLLIPGCCNCCDK8IDO1 | |
| SCHEMBL25606892 | 0.84 | HTR1A (0.44) | SLC22A12EGFRPARP1 | |
| SCHEMBL16156593 | 0.82 | NR4A2 (0.47) | CCNCCDK8GAKEGFRPARP1 | |
| SCHEMBL23911086 | 0.80 | LMNA (0.48) | GAKSLC22A12RIPK2 | |
| SCHEMBL4396762 | 0.79 | KDM4E (0.39) | GAKEGFR | |
| SCHEMBL2512339 | 0.79 | GAK (0.41) | CCNCCDK8GAKSLC22A12RIPK2 | |
| SCHEMBL30074594 | 0.79 | EGFR (0.34) | LPLLIPGEGFR | |
| SCHEMBL25606843 | 0.79 | EGFR (0.34) | LPLLIPGEGFR | |
| SCHEMBL476912 | 0.78 | NCF1 (0.42) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384502-B | Cycloalkyl-substituted amide derivatives, preparation method and medical application thereof | 上海海雁医药科技有限公司 | 2022-11-08 | — | — | CN | disclosed |