Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | CD38 | P28907 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923237 | 0.84 | PARP1 (0.43) | RAB9ANPC1PARP1CD38TP53 | |
| SCHEMBL29923860 | 0.79 | PARP1 (0.49) | RAB9ANPC1PLK1PARP1MAPT | |
| SCHEMBL24915920 | 0.75 | L3MBTL1 (0.37) | RAB9ANPC1PLK1CD38MAPT | |
| SCHEMBL29923496 | 0.70 | RAB9A (0.43) | RAB9ANPC1PARP1MEN1KMT2A | |
| SCHEMBL4518402 | 0.67 | PLK1 (0.59) | RAB9ANPC1PLK1MAPTALDH1A1 | |
| SCHEMBL24915849 | 0.67 | PLK1 (0.37) | RAB9ANPC1PLK1ALDH1A1ALOX12 | |
| SCHEMBL23095470 | 0.66 | GAA (0.53) | RAB9ANPC1PLK1PARP1TP53 | |
| SCHEMBL19219126 | 0.66 | PLK1 (0.53) | RAB9APLK1TP53MAPTALDH1A1 | |
| SCHEMBL10288628 | 0.66 | PLK1 (0.68) | PLK1HDAC6KLKB1 | |
| SCHEMBL19657577 | 0.66 | NR1I2 (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |