Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | CD38 | P28907 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915922 | 0.84 | MEN1 (0.40) | L3MBTL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL24916059 | 0.84 | POLB (0.41) | L3MBTL1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL24915926 | 0.83 | TLR9 (0.42) | TLR8TLR7SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL24915849 | 0.80 | PLK1 (0.37) | L3MBTL1PLK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL24915921 | 0.80 | MTNR1A (0.43) | PLK1SMN1; SMN2CD38MEN1KMT2A | |
| SCHEMBL29924057 | 0.75 | RAB9A (0.42) | PLK1CD38MEN1KMT2AKDM4E | |
| SCHEMBL24916053 | 0.72 | DHFR (0.43) | L3MBTL1KDM4EMAPT | |
| SCHEMBL24916056 | 0.70 | KDM4E (0.34) | L3MBTL1KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL24915919 | 0.69 | HPGD (0.43) | L3MBTL1SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL29923860 | 0.66 | PARP1 (0.49) | PLK1MEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | L3MBTL1 1214/4885PLK1 264/4885TLR8 4298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.