Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924057 | 0.84 | RAB9A (0.42) | PARP1RAB9ASORT1NPC1MEN1 | |
| SCHEMBL28172844 | 0.79 | PARP1 (0.46) | PARP1RAB9ASMN1; SMN2SORT1NPC1 | |
| SCHEMBL17035383 | 0.78 | ACLY (0.48) | PARP1RAB9ASMN1; SMN2SORT1PKM | |
| SCHEMBL29923343 | 0.77 | PARP1 (0.52) | PARP1SMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL2015530 | 0.75 | KDM4E (0.49) | PARP1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL29923496 | 0.73 | RAB9A (0.43) | PARP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL10947807 | 0.72 | HMGB1 (0.47) | RAB9ASMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL29412561 | 0.71 | PARP1 (0.72) | PARP1RAB9AMEN1KMT2ACCR1 | |
| SCHEMBL5319765 | 0.71 | PARP1 (0.72) | PARP1RAB9AMEN1KMT2ACCR1 | |
| SCHEMBL8072226 | 0.71 | GABRP (0.68) | RAB9ASMN1; SMN2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |