Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ESRRB | O95718 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29927681 | 1.00 | CPB2 (0.39) | CPB2PLA2G4ASMYD3KDM4EMAPK1 | |
| SCHEMBL25235849 | 0.81 | CPB2 (0.47) | CPB2PLA2G4ASMYD3KDM4E | |
| SCHEMBL14151866 | 0.74 | PLA2G4A (0.42) | PLA2G4ASMYD3KDM4EMAPK1L3MBTL1 | |
| SCHEMBL24035826 | 0.74 | PLA2G4A (0.37) | CPB2PLA2G4ASMYD3KDM4E | |
| SCHEMBL151394 | 0.72 | SMYD3 (0.50) | CPB2PLA2G4ASMYD3KDM4EL3MBTL1 | |
| SCHEMBL29224232 | 0.72 | PLA2G4A (0.36) | CPB2PLA2G4ASMYD3KDM4E | |
| SCHEMBL29016719 | 0.71 | MEN1 (0.40) | CPB2SMYD3KDM4EMAPK1MEN1 | |
| SCHEMBL3689829 | 0.70 | PLA2G4A (0.40) | PLA2G4ASMYD3KDM4EL3MBTL1 | |
| SCHEMBL23361721 | 0.70 | RAB9A (0.51) | PLA2G4AKDM4EMAPK1L3MBTL1 | |
| SCHEMBL710279 | 0.69 | KDM5A (0.54) | CPB2PLA2G4ASMYD3KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4059933-A1 | AZABENZIMIDAZOLE COMPOUND AND MEDICINE | Nippon Shinyaku Co., Ltd. (JP) | 2022-09-21 | — | — | EP | disclosed |