Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20568110 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPK1CA12CA9RORC | |
| SCHEMBL18163161 | 0.87 | RORC (0.49) | ALDH1A1MAPK1CA12CA9RORC | |
| SCHEMBL102797 | 0.87 | ALDH1A1 (0.60) | ALDH1A1MAPK1RORCPDE7AKMT2A | |
| Hydrochloric Acid SCHEMBL3141636 | 0.85 | ALDH1A1 (0.58) | ALDH1A1MAPK1RORCPDE7AKMT2A | |
| SCHEMBL5182501 | 0.84 | KMT2A (0.59) | ALDH1A1MAPK1RORCPDE7AKMT2A | |
| SCHEMBL3141628 | 0.84 | RORC (0.49) | ALDH1A1MAPK1RORCP2RX1TMPRSS4 | |
| SCHEMBL16045437 | 0.83 | L3MBTL1 (0.60) | ALDH1A1MAPK1RORCPDE7AKMT2A | |
| SCHEMBL2152528 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPK1RORCP2RX1TMPRSS4 | |
| SCHEMBL29250813 | 0.81 | RORC (0.44) | ALDH1A1MAPK1CA12CA9RORC | |
| SCHEMBL16915502 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPK1RORCPDE7AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059132-A1 | METHOD FOR PREPARING 2-SUBSTITUTED ARYLACETONITRILE COMPOUND AND APPLICATION THEREOF | MAXUNITECH INC (CN) | 2025-02-20 | — | — | US | claimed |
| EP-4524127-A1 | METHOD FOR PREPARING 4-NITRO-2-TRIFLUOROMETHYL ACETOPHENONE AND USE THEREOF | Maxunitech Inc. (CN) | 2025-03-19 | — | — | EP | disclosed |
| US-20250059132-A1 | METHOD FOR PREPARING 2-SUBSTITUTED ARYLACETONITRILE COMPOUND AND APPLICATION THEREOF | MAXUNITECH INC (CN) | 2025-02-20 | — | — | US | disclosed |
| US-20250051260-A1 | METHOD FOR PREPARING 4-NITRO-2-(TRIFLUOROMETHYL)ACETOPHENONE AND APPLICATION THEREOF | MAXUNITECH INC (CN) | 2025-02-13 | — | — | US | disclosed |
| CN-115052853-B | Process for preparing 1- [ 4-nitro-2- (trifluoromethyl) phenyl ] alkanone | 巴斯夫农业公司 | 2024-10-25 | — | — | CN | disclosed |
| EP-4103540-A1 | PROCESS FOR THE PREPARATION OF 1-[4-NITRO-2-(TRIFLUOROMETHYL)PHENYL]-ALKANONES | BASF Agro B.V. (NL) | 2022-12-21 | — | — | EP | disclosed |
| CN-115052853-A | Preparation method of 1- [ 4-nitro-2- (trifluoromethyl) phenyl ] alkanone | 巴斯夫农业公司 | 2022-09-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250059132-A1 | METHOD FOR PREPARING 2-SUBSTITUTED ARYLACETONITRILE COMPOUND AND APPLICATION THEREOF | CYP1B1, CYP1A2, CYP2C9 | ALDH1A1 209/4885MAPK1 1760/4885CA12 1579/4885 |
| US-20250051260-A1 | METHOD FOR PREPARING 4-NITRO-2-(TRIFLUOROMETHYL)ACETOPHENONE AND APPLICATION THEREOF | NOX4, NQO1, NDUFV1 | ALDH1A1 154/4885MAPK1 3381/4885CA12 1881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.