SCHEMBL29929296

SCHEMBL29929296

O=C(O)c1cccc(-c2conn2)c1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 2/20 0.37
USP2 O75604 1/20 0.37
TSHR P16473 1/20 0.37
FOLH1 Q04609 1/20 0.37
HNF4A P41235 1/20 0.37
MYC P01106 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
ALOX15 P16050 1/20 0.35
LIG1 P18858 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
AKR1C3 P42330 1/20 0.33
TYMS P04818 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11525911 0.85 RAB9A (0.45) HSD17B10ALDH1A1KDM4EUSP2TSHR
SCHEMBL63603 0.77 HSD17B10 (0.58) HSD17B10ALDH1A1KDM4ETSHRFOLH1
SCHEMBL11363506 0.77 CYP1A2 (0.40) ALDH1A1KDM4EUSP2TSHRHNF4A
SCHEMBL11363516 0.76 TRPA1 (0.36) HNF4ALMNAMAPTNPC1RAB9A
Water SCHEMBL7131144 0.75 HSD17B10 (0.56) HSD17B10ALDH1A1KDM4ETSHRFOLH1
SCHEMBL5554145 0.75 HSD17B10 (0.56) HSD17B10ALDH1A1KDM4ETSHRFOLH1
SCHEMBL673264 0.75 BCAT2 (0.46) ALDH1A1FOLH1HNF4ANPC1RAB9A
SCHEMBL11776499 0.74 BCAT2 (0.53) HSD17B10ALDH1A1KDM4ETSHRLMNA
SCHEMBL6941870 0.73 ALDH1A1 (0.59) HSD17B10ALDH1A1KDM4EFOLH1HNF4A
SCHEMBL5321232 0.73 ALDH1A1 (0.59) HSD17B10ALDH1A1KDM4EFOLH1HNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115816924-A Article having an inorganic substrate and a polymeric film layer 杜邦电子公司 2023-03-21 CN disclosed
CN-115232471-A Polyimide film and electronic device 杜邦电子公司 2022-10-25 CN disclosed