Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823347 | 1.00 | NSD2 (0.44) | NSD2NSD3EGFRKDRKDM4E | |
| SCHEMBL427426 | 0.86 | KDR (0.40) | EGFRKDRKDM4ESLC6A4KMT2A | |
| SCHEMBL5881114 | 0.84 | HPGD (0.55) | NSD2NSD3EGFRKDM4ESLC6A4 | |
| SCHEMBL578735 | 0.84 | L3MBTL1 (0.43) | NSD2NSD3EGFRKDRKDM4E | |
| SCHEMBL31053304 | 0.83 | FBP1 (0.44) | KDM4ESLC6A4KMT2AHPGDL3MBTL1 | |
| SCHEMBL1516692 | 0.83 | FBP1 (0.44) | KDM4ESLC6A4KMT2AHPGDL3MBTL1 | |
| SCHEMBL7934151 | 0.83 | ALDH1A1 (0.45) | NSD2NSD3KDM4ESLC6A4AAK1 | |
| SCHEMBL1311491 | 0.82 | SMN1; SMN2 (0.49) | NSD2NSD3EGFRKDRKDM4E | |
| SCHEMBL14402360 | 0.81 | HPGD (0.47) | KDM4EKMT2AHPGDL3MBTL1 | |
| SCHEMBL7769950 | 0.81 | NSD2 (0.46) | NSD2NSD3KDM4ESLC6A4AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843641-B | NSD3 inhibitor and preparation method and application thereof | 和径医药科技（上海）有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-117843641-A | NSD3 inhibitor and preparation method and application thereof | 和径医药科技（上海）有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-109311887-B | Pyrazolo [1,5-a ] pyrimidinecarboxamide compounds and their use in the treatment of medical conditions | BIAL研发投资股份有限公司 | 2022-09-13 | — | — | CN | disclosed |