Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11451918 | 0.70 | GPR35 (0.50) | CUL4AKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL11451916 | 0.70 | GPR35 (0.50) | CUL4AKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL31525035 | 0.68 | HSD17B10 (0.47) | CUL4AKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL3253975 | 0.68 | HSD17B10 (0.47) | CUL4AKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL29525039 | 0.68 | ALDH1A1 (0.48) | CUL4AKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL16355165 | 0.67 | HSD17B10 (0.67) | KMT2AMEN1L3MBTL1HSD17B10TDP1 | |
| SCHEMBL22566 | 0.67 | HSD17B10 (0.67) | KMT2AMEN1L3MBTL1HSD17B10TDP1 | |
| SCHEMBL29577518 | 0.67 | HSD17B10 (0.67) | KMT2AMEN1L3MBTL1HSD17B10TDP1 | |
| SCHEMBL7186078 | 0.67 | KMT2A (0.45) | CUL4AKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL9595282 | 0.66 | KMT2A (0.47) | CUL4AKDM4EKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226377-B | Antibody drug conjugates comprising an eltrinastine derivative | 法马马有限公司 | 2022-10-18 | — | — | CN | disclosed |