Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 4/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.38 |
| ▸ | FPR1 | P21462 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536493 | 1.00 | PHGDH (0.42) | PHGDHKMT2AMEN1MCHR1POLB | |
| SCHEMBL29932021 | 0.81 | PROKR1 (0.39) | PHGDHHTTFPR2PROKR1GRM5 | |
| SCHEMBL23536198 | 0.81 | GRM2 (0.40) | PHGDHPOLBHTTFPR2PROKR1 | |
| SCHEMBL29932049 | 0.79 | PHGDH (0.39) | PHGDHKMT2AMEN1HTTPROKR1 | |
| SCHEMBL23536190 | 0.79 | PHGDH (0.39) | PHGDHKMT2AMEN1HTTPROKR1 | |
| SCHEMBL29931746 | 0.77 | ALDH1A1 (0.40) | KMT2AMEN1HTTFPR2PROKR1 | |
| SCHEMBL23536504 | 0.70 | DRD4 (0.42) | PHGDHPOLBHTTGRM5LMNA | |
| SCHEMBL29931890 | 0.70 | DRD4 (0.42) | PHGDHPOLBHTTGRM5LMNA | |
| SCHEMBL23536360 | 0.69 | NOTUM (0.63) | KMT2AHTTLMNA | |
| SCHEMBL29932011 | 0.69 | NOTUM (0.63) | KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |