Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29931916 | 0.85 | KMT2A (0.39) | SMN1; SMN2LMNAMEN1KMT2ATHRB | |
| SCHEMBL23536112 | 0.84 | POLB (0.42) | LMNAMEN1KMT2ATHRBRXFP1 | |
| SCHEMBL29948574 | 0.84 | POLB (0.42) | LMNAMEN1KMT2ATHRBRXFP1 | |
| SCHEMBL29931842 | 0.80 | MEN1 (0.33) | SMN1; SMN2LMNAMEN1KMT2ACRHBP | |
| SCHEMBL29932038 | 0.79 | HTR1A (0.43) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL29932062 | 0.77 | ALDH1A1 (0.33) | SMN1; SMN2LMNAMEN1KMT2ARXFP1 | |
| SCHEMBL29932033 | 0.77 | MAPT (0.34) | SMN1; SMN2LMNAMEN1KMT2APOLB | |
| SCHEMBL29931835 | 0.77 | PGR (0.36) | SMN1; SMN2LMNAMEN1KMT2ACRHBP | |
| SCHEMBL23536117 | 0.74 | POLB (0.41) | SMN1; SMN2LMNAKMT2ATHRBRXFP1 | |
| SCHEMBL29931921 | 0.74 | POLB (0.41) | SMN1; SMN2LMNAKMT2ATHRBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |