Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833398 | 0.74 | CYP1A2 (0.33) | MAOATDP1 | |
| SCHEMBL1576553 | 0.74 | GPR3 (0.34) | ALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL8573686 | 0.71 | ALDH1A1 (0.38) | KDM4EGAAALDH1A1HSD17B10MAPT | |
| SCHEMBL31307786 | 0.69 | ALDH1A1 (0.45) | KDM4ECYP3A4ALDH1A1HSD17B10MAPT | |
| SCHEMBL10833787 | 0.68 | TDP1 (0.36) | KDM4ECYP3A4ALDH1A1MAPTGLA | |
| SCHEMBL11437065 | 0.66 | GAA (0.41) | KDM4EGAACYP3A4ALDH1A1HPGD | |
| SCHEMBL30286606 | 0.63 | CYP2A6 (0.33) | ALDH1A1HSD17B10TDP1TSHR | |
| SCHEMBL205562 | 0.63 | CYP2A6 (0.33) | ALDH1A1HSD17B10TDP1TSHR | |
| SCHEMBL221530 | 0.59 | KDM4E (1.00) | KDM4EGAAPDPK1CYP3A4ALDH1A1 | |
| SCHEMBL31416835 | 0.59 | KDM4E (1.00) | KDM4EGAAPDPK1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948570-A1 | METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1999-10-13 | — | — | EP | claimed |
| WO-1998023690-A1 | METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1998-06-04 | — | — | WO | claimed |
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8017554-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest | BASF SE (DE) | 2011-09-13 | — | — | US | disclosed |
| US-20100167922-A1 | 3-Amino-1,2-benzisothiazole Compounds for Combating Animal Pest | BASF SE (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| EP-2064196-A2 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF Aktiengesellschaft (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-2003975-A1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST | BASF SE (DE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2008090048-A2 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2008-07-31 | — | — | WO | disclosed |
| WO-2007113119-A1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST | BASF SE (DE) | 2007-10-11 | — | — | WO | disclosed |
| EP-0948570-A1 | METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998023690-A1 | METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BPNT1, BCAT1, TGFBR1 | KDM4E 3057/4885GAA 3807/4885PDPK1 1982/4885 |
| US-20100167922-A1 | 3-Amino-1,2-benzisothiazole Compounds for Combating Animal Pest | BPNT1, AADAT, BCAT1 | KDM4E 1001/4885GAA 4366/4885PDPK1 2432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.