SCHEMBL29933731

SCHEMBL29933731

COc1cc(/C=C/C(=O)O[C@H]2Cc3cc4ccc(=O)oc4cc3OC2(C)C)ccc1OC(C)=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.65
▸ GAA P10253 2/20 0.49
▸ MGAM O43451 1/20 0.49
▸ SI P14410 1/20 0.49
▸ PTPN1 P18031 1/20 0.49
▸ ACHE P22303 1/20 0.49
▸ MGAM2 Q2M2H8 1/20 0.49
▸ CA9 Q16790 4/20 0.45
▸ CA12 O43570 3/20 0.45
▸ JUN P05412 1/20 0.44
▸ NFKB1 P19838 1/20 0.44
▸ KDM4E B2RXH2 5/20 0.43
▸ HPGD P15428 4/20 0.43
▸ ALDH1A1 P00352 3/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ HDAC3 O15379 1/20 0.42
▸ HDAC1 Q13547 1/20 0.42
▸ HDAC2 Q92769 1/20 0.42
▸ HDAC10 Q969S8 1/20 0.42
▸ HDAC11 Q96DB2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24758311 1.00 MAOA (0.65) MAOAGAAMGAMSIPTPN1
SCHEMBL24756833 0.94 MAOA (0.67) MAOAGAAMGAMSIPTPN1
SCHEMBL31346495 0.92 MAOA (0.55) MAOAGAAMGAMSIPTPN1
SCHEMBL14303568 0.91 MAOA (0.66) MAOAGAAMGAMSIPTPN1
SCHEMBL29933810 0.90 MAOA (0.65) MAOAGAAMGAMSIPTPN1
SCHEMBL18800809 0.90 MAOA (0.65) MAOAGAAMGAMSIPTPN1
SCHEMBL4744257 0.88 MAOA (0.69) MAOAGAAMGAMSIPTPN1
SCHEMBL4744259 0.88 MAOA (0.69) MAOAGAAMGAMSIPTPN1
SCHEMBL4740874 0.86 MAOA (0.66) MAOAGAAMGAMSIPTPN1
SCHEMBL24756232 0.86 MAOA (0.66) MAOAGAAMGAMSIPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025048007-A1 COMPOSITION FOR PREVENTING OR TREATING ALZHEIMER'S DISEASE, CONTAINING NOVEL COMPOUND (주)피알지에스앤텍 2025-03-06 — — WO claimed
WO-2025023339-A1 COMPOSITION CONTAINING NOVEL COMPOUND FOR PREVENTING OR TREATING PARKINSON'S DISEASE (주)피알지에스앤텍 2025-01-30 — — WO claimed
EP-4056573-B1 USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS PRG S&TECH INC (KR) 2024-11-06 — — EP claimed
US-20220402930-A1 USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS PRG S&TECH INC. (KR) 2022-12-22 — — US claimed
EP-4056573-A1 USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS PRG S&Tech Inc. (KR) 2022-09-14 — — EP claimed
WO-2025048007-A1 COMPOSITION FOR PREVENTING OR TREATING ALZHEIMER'S DISEASE, CONTAINING NOVEL COMPOUND (주)피알지에스앤텍 2025-03-06 — — WO disclosed
WO-2025023339-A1 COMPOSITION CONTAINING NOVEL COMPOUND FOR PREVENTING OR TREATING PARKINSON'S DISEASE (주)피알지에스앤텍 2025-01-30 — — WO disclosed
EP-4056573-B1 USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS PRG S&TECH INC (KR) 2024-11-06 — — EP disclosed
US-20220402930-A1 USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS PRG S&TECH INC. (KR) 2022-12-22 — — US disclosed
EP-4056573-A1 USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS PRG S&Tech Inc. (KR) 2022-09-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402930-A1 USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS SOD1, SLC75A1, SLC43A1 MAOA 2110/4885GAA 1104/4885MGAM 3456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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