Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | XPO1 | O14980 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29934354 | 0.85 | XPO1 (0.47) | XDHCTSSXPO1KMOKDM4E | |
| SCHEMBL1592508 | 0.85 | XPO1 (0.47) | XDHCTSSXPO1KMOKDM4E | |
| SCHEMBL1592510 | 0.84 | XDH (0.45) | XDHCTSSKMOKDM4EALDH1A1 | |
| SCHEMBL30346302 | 0.68 | XPO1 (0.63) | XDHXPO1ADORA2A | |
| SCHEMBL4787 | 0.68 | CTSS (0.60) | XDHCTSSKMOKDM4EALDH1A1 | |
| SCHEMBL6256565 | 0.68 | CTSS (0.60) | XDHCTSSKMOKDM4EALDH1A1 | |
| SCHEMBL2615262 | 0.68 | CTSS (0.60) | XDHCTSSKMOKDM4EALDH1A1 | |
| SCHEMBL3999574 | 0.68 | CTSS (0.60) | XDHCTSSKMOKDM4EALDH1A1 | |
| SCHEMBL2304614 | 0.68 | CTSS (0.56) | XDHCTSSKMOKDM4EALDH1A1 | |
| SCHEMBL14152109 | 0.67 | KMO (0.66) | XDHCTSSKMOKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4074704-A1 | QUINOLINE COMPOUNDS WITH ANTI-CANCER ACTIVITY | CanBas Co., Ltd. (JP) | 2022-10-19 | — | — | EP | disclosed |