Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.30 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31462412 | 0.90 | FFAR1 (0.35) | CYP11B2MAPTGSK3BFFAR1CHRM1 | |
| SCHEMBL29934919 | 0.86 | CYP11B2 (0.39) | CYP11B2MAPTGSK3BHSP90AA1KCNH2 | |
| SCHEMBL31462409 | 0.79 | CYP11B2 (0.36) | CYP11B2MAPTGSK3BHSP90AA1KCNH2 | |
| SCHEMBL29932952 | 0.78 | CNR1 (0.42) | CHRM1 | |
| SCHEMBL29932961 | 0.78 | CNR1 (0.42) | CHRM1 | |
| SCHEMBL31359374 | 0.76 | MKNK1 (0.38) | CYP11B2PTK2KCNH2 | |
| SCHEMBL29934041 | 0.75 | KCNH2 (0.43) | CYP11B2MAPTKCNH2KCNA5KMT2A | |
| SCHEMBL28884710 | 0.73 | KDM4C (0.43) | CYP11B2KCNH2KCNA5 | |
| SCHEMBL29934030 | 0.73 | KDM4C (0.43) | CYP11B2KCNH2KCNA5 | |
| SCHEMBL28884685 | 0.72 | ABL1 (0.44) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4074376-A1 | COMPOUND SERVING AS PDGF RECEPTOR KINASE INHIBITOR, AND COMPOSITION | Nippon Shinyaku Co., Ltd. (JP) | 2022-10-19 | — | — | EP | disclosed |