Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | RXRG | P48443 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936760 | 0.85 | MAPT (0.52) | ALDH1A1MAPTHPGDMAPK1HSD17B10 | |
| SCHEMBL29936962 | 0.75 | MAPT (0.48) | ALDH1A1MAPTHPGDMAPK1MEN1 | |
| SCHEMBL29936878 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL2470879 | 0.74 | NOTUM (0.62) | NOTUMALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL25332785 | 0.74 | SLC6A3 (0.50) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL29936641 | 0.73 | EPHX2 (0.45) | ALDH1A1HPGDMAPK1MEN1KMT2A | |
| SCHEMBL8659227 | 0.72 | ERAP1 (0.46) | ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6728154 | 0.72 | PTGS2 (0.54) | S1PR1 | |
| SCHEMBL28835940 | 0.72 | SLC6A2 (0.47) | ALDH1A1MAPTMAPK1HSD17B10MEN1 | |
| SCHEMBL17224683 | 0.71 | NOTUM (0.46) | NOTUMALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010600-B | Method for synthesizing polyfluoroaryl carboxylic acid compound based on aryl fluorocarbon bond carboxylation reaction | 四川大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-115010600-A | Method for synthesizing polyfluoroaryl carboxylic acid compounds based on aryl fluorocarbon bond carboxylation reaction | 四川大学 | 2022-09-06 | — | — | CN | disclosed |