Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637165 | 0.77 | RAB9A (0.44) | TDP1ALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL11670896 | 0.76 | TDP1 (0.55) | L3MBTL1TDP1ATMALDH1A1KDM4E | |
| SCHEMBL2031522 | 0.75 | SYK (0.38) | L3MBTL1ALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL10686148 | 0.73 | RAB9A (0.44) | TDP1ALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL21241039 | 0.71 | ALDH1A1 (0.41) | L3MBTL1ATMALDH1A1KDM4EKMT2A | |
| SCHEMBL9061345 | 0.70 | TDP1 (0.47) | L3MBTL1TDP1ATMALDH1A1KDM4E | |
| SCHEMBL57851 | 0.70 | TRPM8 (0.43) | ALDH1A1KDM4EKMT2AHSD17B10MAPT | |
| SCHEMBL5788823 | 0.70 | RAB9A (0.58) | L3MBTL1ALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL14979242 | 0.70 | CES2 (0.44) | TDP1ALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL11670902 | 0.69 | ATM (0.50) | L3MBTL1TDP1ATMALDH1A1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220227-A1 | TETRAHYDROPYRIDOPYRIMIDINE COMPOUND | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2022-10-20 | — | — | WO | disclosed |