SCHEMBL2993840

SCHEMBL2993840

O=S(=O)(F)C(F)(F)C(F)(F)S(=O)(=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.42
APOBEC3G Q9HC16 1/20 0.40
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA5A P35218 2/20 0.39
CA9 Q16790 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA12 O43570 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA7 P43166 1/20 0.39
PLA2G7 Q13093 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776228 0.82 HTR6 (0.46) HTR6APOBEC3GCA1CA2CA5A
SCHEMBL5014762 0.81 TSHR (0.48) HTR6APOBEC3GCA1CA2CA5A
SCHEMBL2991893 0.80 HTR6 (0.44) HTR6APOBEC3GCA1CA2CA5A
SCHEMBL5015146 0.78 HTR6 (0.42) HTR6APOBEC3GCA1CA2CA5A
SCHEMBL776908 0.78 HTR6 (0.42) HTR6APOBEC3GCA1CA2CA5A
SCHEMBL777838 0.77 CA2 (0.44) HTR6APOBEC3GCA1CA2CA5A
SCHEMBL777153 0.77 HTR6 (0.50) HTR6APOBEC3GCA1CA2CA5A
SCHEMBL13036722 0.75 ALDH1A1 (0.36) CA1CA2CA5ACA9ALDH1A1
SCHEMBL5664875 0.75 HTR6 (0.48) HTR6APOBEC3GCA1CA2CA5A
SCHEMBL11559001 0.74 KEAP1 (0.48) CA1CA2ALDH1A1IL1RNKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2084166-B1 PREPARATION PROCESS OF AROMATIC SULFONYLIMIDES INST NAT POLYTECHNIQUE DE GRENOBLE (FR) 2017-11-22 EP disclosed
US-8853448-B2 Aromatic sulfonylimides, preparation thereof and use thereof as electrolyte INSTITUT NATIONAL POLYTECHNIQUE DE GRENOBLE (FR) 2014-10-07 US disclosed
US-8853448-B2 Aromatic sulfonylimides, preparation thereof and use thereof as electrolyte INSTITUT NATIONAL POLYTECHNIQUE DE GRENOBLE (FR) 2014-10-07 US disclosed
US-8853448-B2 Aromatic sulfonylimides, preparation thereof and use thereof as electrolyte INSTITUT NATIONAL POLYTECHNIQUE DE GRENOBLE (FR) 2014-10-07 US disclosed
US-20100174113-A1 AROMATIC SULPHONYLIMIDES, PREPARATION THEREOF AND USE THEREOF AS ELECTROLYTE INSTITUT NATIONAL POLYTECHNIQUE DE GRENOBLE (FR) 2010-07-08 US disclosed
US-20100174113-A1 AROMATIC SULPHONYLIMIDES, PREPARATION THEREOF AND USE THEREOF AS ELECTROLYTE INSTITUT NATIONAL POLYTECHNIQUE DE GRENOBLE (FR) 2010-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100174113-A1 AROMATIC SULPHONYLIMIDES, PREPARATION THEREOF AND USE THEREOF AS ELECTROLYTE AFF2, ARSA, FGFR2 HTR6 3467/4885APOBEC3G 4408/4885CA1 1507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.