SCHEMBL777153

SCHEMBL777153

O=S(=O)(c1ccccc1)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
LMNA P02545 2/20 0.48
MAPK1 P28482 2/20 0.48
HTT P42858 1/20 0.48
ALDH1A1 P00352 2/20 0.48
PTPRZ1 P23471 1/20 0.47
APOBEC3G Q9HC16 1/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA5A P35218 2/20 0.46
CA9 Q16790 2/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA12 O43570 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA7 P43166 1/20 0.46
PLA2G7 Q13093 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776228 0.85 HTR6 (0.46) HTR6SMN1; SMN2LMNAMAPK1HTT
SCHEMBL5664875 0.82 HTR6 (0.48) HTR6SMN1; SMN2ALDH1A1APOBEC3GCA1
SCHEMBL8519013 0.82 ALDH1A1 (0.57) SMN1; SMN2LMNAMAPK1HTTALDH1A1
SCHEMBL13088070 0.81 LMNA (0.43) HTR6SMN1; SMN2LMNAMAPK1HTT
SCHEMBL8941634 0.81 HTT (0.57) HTR6SMN1; SMN2LMNAMAPK1HTT
SCHEMBL775525 0.80 HTR6 (0.46) HTR6SMN1; SMN2ALDH1A1APOBEC3GCA1
SCHEMBL2853702 0.80 HTR6 (0.46) HTR6SMN1; SMN2ALDH1A1APOBEC3GCA1
SCHEMBL6053237 0.80 HSD11B1 (0.47) HTR6SMN1; SMN2ALDH1A1APOBEC3GCA1
SCHEMBL18986850 0.80 ALDH1A1 (0.48) HTR6SMN1; SMN2LMNAHTTALDH1A1
SCHEMBL6709353 0.78 HSD11B1 (0.40) ALDH1A1APOBEC3GTSHRKIF11HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115417787-A Extractant for rapidly and efficiently separating and extracting strontium and preparation method thereof 四川大学 2022-12-02 CN claimed
CN-114899487-A Electrolyte with phenyl trifluoromethanesulfone as additive and lithium ion battery thereof 湖南大学 2022-08-12 CN claimed
WO-2022093716-A1 SYMMETRICAL OR ASYMMETRICAL ALKYLSULFONYL IMIDE OR CYCLIC ALKYLENE SULFONYLIMIDE SALTS AS CATHODE ADDITIVES, ELECTROLYTE ADDITIVES, OR SI ANODE ADDITIVES FOR SI ANODE-BASED LI-ION CELLS ENEVATE CORPORATION (US) 2022-05-05 WO claimed
US-20220131193-A1 SYMMETRICAL OR ASYMMETRICAL ALKYLSULFONYL IMIDE OR CYCLIC ALKYLENE SULFONYLIMIDE SALTS AS CATHODE ADDITIVES, ELECTROLYTE ADDITIVES, OR SI ANODE ADDITIVES FOR SI ANODE-BASED LI-ION CELLS ENEVATE CORPORATION 2022-04-28 US claimed
CN-112538005-B Preparation method of 1,3, 5-trimethoxybenzene 南京艾德凯腾生物医药有限责任公司 2022-04-12 CN claimed
CN-109420525-B Metal iridium catalyst of 2, 2' -bis-benzimidazole ligand and method for synthesizing N-methylated primary amine by using metal iridium catalyst 南京理工大学 2021-10-08 CN claimed
CN-112538005-A Preparation method of 1,3, 5-trimethoxybenzene 南京艾德凯腾生物医药有限责任公司 2021-03-23 CN claimed
CN-108026610-B Method for separating americium from liquid radioactive substances and separating americium from rare earth elements 俄罗斯国家原子能公司 2020-05-12 CN claimed
EP-3296411-B1 METHOD FOR ISOLATING AMERICIUM FROM LIQUID RADIOACTIVE WASTE AND FOR SEPARATING AMERICIUM FROM RARE EARTH ELEMENTS STATE ATOMIC ENERGY CORP ROSATOM BEHALF RUSSIAN FEDERATION (RU) 2020-03-18 EP claimed
US-10590513-B2 Method for isolating americium from liquid radioactive waste and for separating americium from rare earth elements STATE ATOMIC ENERGY CORPORATION “ROSATOM” ON BEHALF OF THE RUSSIAN FEDERATION (RU) 2020-03-17 US claimed
WO-2000045635-A1 THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2000-08-10 WO claimed
WO-2000025768-A1 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2000-05-11 WO claimed
US-5672760-A OBTAINING A PHOTOABSORBER-CONTAINING ACRYLIC POLYMER BY USING N-2-HYDROXYETHYL-N-ETHYL ANILINE TO OBTAIN 4-((2-HYDROXYETHYL)ETHYLAMINO)-4'-(TRIFLUOROMETHYLSULFONYL)-TOLANE WHICH REACTS WITH A POLYMERIZABLE METHACRYLIC ACID INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-09-30 US claimed
US-4771062-A ENZYME INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 1988-09-13 US claimed
EP-0240680-A1 Diaryl sulfide derivatives BAYER AG (DE) 1987-10-14 EP claimed
US-4659720-A POULTRY ANTIPROTOZOA AGENT MERCK & CO., INC. (US) 1987-04-21 US claimed
EP-0113570-B1 5-(AMINO OR SUBSTITUTED AMINO) IMIDAZOLES MERCK & CO. INC. (US) 1987-02-25 EP claimed
US-4622330-A Antiprotozoal 3-amino or substituted amino pyrazoles MERCK & CO., INC. (US) 1986-11-11 US claimed
EP-0113570-A1 5-(Amino or substituted amino) imidazoles MERCK & CO. INC. (US) 1984-07-18 EP claimed
US-3941453-A Birefringent compounds used in Kerr cells U.S. PHILIPS CORPORATION (US) 1976-03-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220131193-A1 SYMMETRICAL OR ASYMMETRICAL ALKYLSULFONYL IMIDE OR CYCLIC ALKYLENE SULFONYLIMIDE SALTS AS CATHODE ADDITIVES, ELECTROLYTE ADDITIVES, OR SI ANODE ADDITIVES FOR SI ANODE-BASED LI-ION CELLS HCN2, IDH2, KCNJ1 HTR6 4628/4885SMN1; SMN2 637/4885LMNA 1751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.