SCHEMBL29938995

SCHEMBL29938995

CCCCCCCCOC(=O)[C@H](CCC(=O)C=[N+]=[N-])NC(=O)[C@H](CCC(=O)C=[N+]=[N-])NC(=O)CC[C@H](N)C(=O)OCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 15/20 0.55
KMT2A Q03164 2/20 0.37
FAAH O00519 1/20 0.37
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27093839 0.94 NOD1 (0.64) NOD1
SCHEMBL27093828 0.94 NOD1 (0.64) NOD1
SCHEMBL30919307 0.82 NOD1 (0.44) NOD1KMT2APOLB
SCHEMBL30919275 0.82 NOD1 (0.44) NOD1KMT2APOLB
SCHEMBL27094761 0.81 NOD1 (0.49) NOD1
SCHEMBL27094762 0.81 NOD1 (0.49) NOD1
SCHEMBL30919269 0.81 NOD1 (0.35) NOD1KMT2APOLB
SCHEMBL30919281 0.80 LTA4H (0.36) NOD1KMT2APOLB
SCHEMBL30919314 0.76 SMN1; SMN2 (0.35) NOD1
SCHEMBL30919306 0.76 NOD1 (0.33) NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240398962-A1 DENDRIMER-GLUTAMINE ANTAGONIST CONJUGATES AND METHODS OF USE THEREOF INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY (CZ) 2024-12-05 US disclosed
EP-4322961-A1 DENDRIMER-GLUTAMINE ANTAGONIST CONJUGATES AND METHODS OF USE THEREOF The Johns Hopkins University (US) 2024-02-21 EP disclosed
WO-2022221490-A1 DENDRIMER-GLUTAMINE ANTAGONIST CONJUGATES AND METHODS OF USE THEREOF THE JOHNS HOPKINS UNIVERSITY (US) 2022-10-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240398962-A1 DENDRIMER-GLUTAMINE ANTAGONIST CONJUGATES AND METHODS OF USE THEREOF GLUL, GLS, GRM2 NOD1 781/4885KMT2A 398/4885FAAH 2652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.