Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 14/20 | 0.62 |
| ▸ | CLK2 | P49760 | 5/20 | 0.62 |
| ▸ | CDK7 | P50613 | 2/20 | 0.62 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.62 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.62 |
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.62 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.62 |
| ▸ | PAK4 | O96013 | 1/20 | 0.62 |
| ▸ | ABL1 | P00519 | 1/20 | 0.62 |
| ▸ | LCK | P06239 | 1/20 | 0.62 |
| ▸ | FYN | P06241 | 1/20 | 0.62 |
| ▸ | CSF1R | P07333 | 1/20 | 0.62 |
| ▸ | RET | P07949 | 1/20 | 0.62 |
| ▸ | IGF1R | P08069 | 1/20 | 0.62 |
| ▸ | MET | P08581 | 1/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10213963 | 0.84 | JAK2 (0.69) | MAP2K4DYRK1ACLK2CDK7LRRK2 | |
| SCHEMBL30588952 | 0.84 | JAK2 (0.69) | MAP2K4DYRK1ACLK2CDK7LRRK2 | |
| SCHEMBL5514698 | 0.84 | MKNK1 (0.72) | MAP2K4DYRK1ACLK2CDK7LRRK2 | |
| SCHEMBL27968550 | 0.83 | MKNK1 (0.71) | MAP2K4DYRK1ACLK2CDK7CHEK1 | |
| SCHEMBL14689480 | 0.79 | PIM1 (0.78) | DYRK1ACLK2PIM1CLK3 | |
| SCHEMBL16284624 | 0.78 | TLR8 (0.59) | DYRK1ACLK2CDK7LRRK2CHEK1 | |
| SCHEMBL19188029 | 0.78 | JAK2 (0.57) | MAP2K4DYRK1ACLK2LRRK2DAPK3 | |
| SCHEMBL22819364 | 0.78 | MAP2K4 (1.00) | MAP2K4DYRK1ACLK2LRRK2PIM1 | |
| SCHEMBL12907433 | 0.78 | MKNK1 (0.51) | MAP2K4DYRK1ACDK7CHEK1JAK2 | |
| SCHEMBL760763 | 0.77 | DYRK1A (0.65) | MAP2K4DYRK1ACLK2CDK7LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |