Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 4/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 6/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MPL | P40238 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27500727 | 0.83 | PARP14 (0.49) | JAK2TP53MAPTHTTKLK7 | |
| SCHEMBL15560416 | 0.81 | KIF11 (0.47) | JAK2TP53MAPTHTTKLK7 | |
| SCHEMBL4786156 | 0.80 | SLC22A6 (0.55) | JAK2TP53MAPTHTTKLK7 | |
| SCHEMBL299311 | 0.79 | PARP14 (0.47) | JAK2TP53MAPTHTTKLK7 | |
| SCHEMBL2429422 | 0.78 | PARP14 (0.51) | JAK2TP53MAPTHTTKLK7 | |
| SCHEMBL29001995 | 0.78 | KIF11 (0.44) | JAK2TP53MAPTHTTKLK7 | |
| SCHEMBL31400290 | 0.78 | PBRM1 (0.50) | JAK2TP53MAPTHTTKLK7 | |
| SCHEMBL27875227 | 0.78 | KMT2A (0.55) | JAK2TP53MAPTHTTKLK7 | |
| SCHEMBL1508109 | 0.77 | TYMS (0.56) | JAK2MAPTTYMSTHRATHRB | |
| SCHEMBL30342255 | 0.77 | TYMS (0.56) | JAK2MAPTTYMSTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713583-B2 | INTRAOCULAR LENSES, INCLUDE CROSS- LINKED POLYMERIC MATERIALS HAVING A FIRST CONSTITUENT DERIVED FROM MONOMERIC ACRYLATES, METHACRYLATES AND SECOND CONSTITUENT AS A CROSS-LINKED POLYMERIC MATERIAL HAVING BRANCHED CHAIN ALKYL GROUP | ADVANCED MEDICAL OPTICS, INC. | 2004-03-30 | — | — | US | claimed |
| EP-1137956-A1 | INTRAOCULAR LENSES MADE FROM POLYMERIC COMPOSITIONS | Allergan Sales, Inc. (US) | 2001-10-04 | — | — | EP | claimed |
| US-20010005743-A1 | Intraocular lenses made from polymeric compositions | ALLERGAN SALES, INC. (US) | 2001-06-28 | — | — | US | claimed |
| US-6241766-B1 | Intraocular lenses made from polymeric compositions | ALLERGAN SALES, INC. | 2001-06-05 | — | — | US | claimed |
| WO-2000026698-B1 | INTRAOCULAR LENSES MADE FROM POLYMERIC COMPOSITIONS | ALLERGAN SALES INC (US) | 2000-07-13 | — | — | WO | claimed |
| WO-2000026698-A1 | INTRAOCULAR LENSES MADE FROM POLYMERIC COMPOSITIONS | ALLERGAN SALES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
| CN-113906068-B | Resin composition for optical modeling | 可乐丽则武齿科株式会社 | 2025-02-25 | — | — | CN | disclosed |
| CN-112898735-A | Anti-brittle-cracking parachute alicyclic epoxy resin injection material for hard composite insulator and preparation method thereof | 浙江紫电新材料有限公司 | 2021-06-04 | — | — | CN | disclosed |
| EP-3234021-A1 | PHOTOPOLYMER COMPRISING A NEW CLASS OF PHOTO INITIATOR | Covestro Deutschland AG (DE) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096639-A1 | PHOTOPOLYMER COMPRISING A NEW CLASS OF PHOTO INITIATOR | COVESTRO DEUTSCHLAND AG (DE) | 2016-06-23 | — | — | WO | disclosed |
| CN-105062063-A | Antimicrobial flame-retardant electrician insulating glove material | GONG CANFENG | 2015-11-18 | — | — | CN | disclosed |
| US-20150166641-A1 | Compositions and Methods for the Removal of Biofilms | UNIV SOUTHERN CALIFORNIA (US) | 2015-06-18 | — | — | US | disclosed |
| US-8785627-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20060110430-A1 | Copolymerizable azo compounds and articles containing them | Johnson & Johnson Surgical Vision, Inc. | 2006-05-25 | — | — | US | disclosed |
| US-6713583-B2 | INTRAOCULAR LENSES, INCLUDE CROSS- LINKED POLYMERIC MATERIALS HAVING A FIRST CONSTITUENT DERIVED FROM MONOMERIC ACRYLATES, METHACRYLATES AND SECOND CONSTITUENT AS A CROSS-LINKED POLYMERIC MATERIAL HAVING BRANCHED CHAIN ALKYL GROUP | ADVANCED MEDICAL OPTICS, INC. | 2004-03-30 | — | — | US | disclosed |
| EP-1137956-A1 | INTRAOCULAR LENSES MADE FROM POLYMERIC COMPOSITIONS | Allergan Sales, Inc. (US) | 2001-10-04 | — | — | EP | disclosed |
| US-20010005743-A1 | Intraocular lenses made from polymeric compositions | ALLERGAN SALES, INC. (US) | 2001-06-28 | — | — | US | disclosed |
| US-6241766-B1 | Intraocular lenses made from polymeric compositions | ALLERGAN SALES, INC. | 2001-06-05 | — | — | US | disclosed |
| WO-2000026698-A1 | INTRAOCULAR LENSES MADE FROM POLYMERIC COMPOSITIONS | ALLERGAN SALES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| US-5132430-A | From acrylic esters with pendant halogenated carbazole groups, optical devices | POLAROID CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166641-A1 | Compositions and Methods for the Removal of Biofilms | FCGR3B, FGB, CD47 | JAK2 3439/4885TP53 1158/4885MAPT 2225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.