Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946017 | 0.87 | MEN1 (0.48) | GPR119PRMT5KDM4EALDH1A1HPGD | |
| SCHEMBL29946020 | 0.87 | MEN1 (0.48) | GPR119PRMT5KDM4EALDH1A1HPGD | |
| SCHEMBL29945994 | 0.87 | GPR119 (0.46) | GPR119JAK2JAK3PTK2PRMT5 | |
| SCHEMBL29945852 | 0.86 | GPR119 (0.53) | GPR119JAK2JAK3PTK2EGLN2 | |
| SCHEMBL13153867 | 0.78 | GPR119 (0.64) | GPR119 | |
| SCHEMBL29946087 | 0.77 | CYP19A1 (0.39) | JAK2JAK3PTK2PRMT5USP2 | |
| SCHEMBL20266517 | 0.77 | GPR119 (0.53) | GPR119PRMT5 | |
| SCHEMBL29945870 | 0.77 | SMN1; SMN2 (0.49) | GPR119MAPT | |
| SCHEMBL6132557 | 0.76 | GPR119 (0.64) | GPR119JAK2JAK3PTK2EGLN2 | |
| SCHEMBL29945962 | 0.76 | GPR119 (0.53) | GPR119JAK2JAK3PTK2EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |