Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | VEGFA | P15692 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946020 | 1.00 | MEN1 (0.48) | MEN1KMT2ANPSR1HPGDUSP2 | |
| SCHEMBL29945994 | 0.90 | GPR119 (0.46) | MEN1KMT2ANPSR1HPGDCNR1 | |
| SCHEMBL29945795 | 0.87 | GPR119 (0.49) | MEN1KMT2ANPSR1HPGDUSP2 | |
| SCHEMBL29945924 | 0.85 | TRPV3 (0.44) | MEN1KMT2ANPSR1HPGDUSP2 | |
| SCHEMBL18176190 | 0.80 | MEN1 (0.57) | MEN1KMT2ANPSR1HPGDUSP2 | |
| SCHEMBL29945870 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAGPR119TP53THRB | |
| SCHEMBL25731609 | 0.76 | GPR119 (0.50) | GPR119THRBHTTKDM4E | |
| SCHEMBL29946091 | 0.76 | KDM4E (0.50) | MEN1KMT2ANPSR1HPGDUSP2 | |
| SCHEMBL8024321 | 0.76 | GPR119 (0.46) | MEN1KMT2ANPSR1HPGDUSP2 | |
| SCHEMBL16827756 | 0.75 | MEN1 (0.48) | MEN1KMT2ANPSR1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |