Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946020 | 0.90 | MEN1 (0.48) | GPR119TP53CNR1PRMT5ALDH1A1 | |
| SCHEMBL29946017 | 0.90 | MEN1 (0.48) | GPR119TP53CNR1PRMT5ALDH1A1 | |
| SCHEMBL29945795 | 0.87 | GPR119 (0.49) | GPR119PRMT5ALDH1A1JAK2JAK3 | |
| SCHEMBL29945870 | 0.87 | SMN1; SMN2 (0.49) | GPR119TP53TRPV3LMNASMN1; SMN2 | |
| SCHEMBL29945924 | 0.81 | TRPV3 (0.44) | TP53POLBCNR1CNR2ALDH1A1 | |
| SCHEMBL18418198 | 0.80 | MGLL (0.57) | GPR119TP53POLBALDH1A1LMNA | |
| SCHEMBL29945852 | 0.79 | GPR119 (0.53) | GPR119TRPV3JAK2JAK3PTK2 | |
| SCHEMBL13590834 | 0.76 | GPR119 (0.52) | GPR119TP53POLBPRMT5MEN1 | |
| SCHEMBL29946091 | 0.76 | KDM4E (0.50) | GPR119ALDH1A1TRPV3MEN1KMT2A | |
| SCHEMBL25731609 | 0.76 | GPR119 (0.50) | GPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |