Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.53 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945870 | 0.89 | SMN1; SMN2 (0.49) | GPR119DPP4TRPV3MAPTSMN1; SMN2 | |
| SCHEMBL29945924 | 0.87 | TRPV3 (0.44) | DPP4TRPV3MAPTSMN1; SMN2 | |
| SCHEMBL29945795 | 0.86 | GPR119 (0.49) | GPR119EGLN2JAK2JAK3PTK2 | |
| SCHEMBL24455270 | 0.81 | GPR119 (0.57) | GPR119TRPV3 | |
| SCHEMBL29556921 | 0.81 | GPR119 (0.56) | GPR119 | |
| SCHEMBL24498579 | 0.81 | GPR119 (0.56) | GPR119TRPV3 | |
| SCHEMBL20266521 | 0.81 | GPR119 (0.56) | GPR119 | |
| SCHEMBL22936354 | 0.80 | GPR119 (0.58) | GPR119 | |
| SCHEMBL29945896 | 0.80 | HTR6 (0.37) | GPR119JAK2JAK3 | |
| SCHEMBL29945994 | 0.79 | GPR119 (0.46) | GPR119JAK2JAK3PTK2TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |