Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642296 | 1.00 | KAT6A (0.47) | KAT6ABRPF1HPGDKDM4EALDH1A1 | |
| SCHEMBL10644835 | 0.84 | KAT6A (0.49) | KAT6AHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL698709 | 0.83 | KDM4E (0.61) | KAT6AHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10526573 | 0.83 | KAT6A (0.47) | KAT6AHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL16958039 | 0.82 | KAT6A (0.42) | KAT6AHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6459628 | 0.81 | KAT6A (0.46) | KAT6AHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL879722 | 0.81 | ALDH1A1 (0.52) | KAT6AHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL16958399 | 0.80 | KAT6A (0.45) | KAT6AHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29772247 | 0.80 | CES2 (0.68) | KAT6AHPGDALDH1A1CES2BCHE | |
| SCHEMBL717464 | 0.80 | CES2 (0.68) | KAT6AHPGDALDH1A1CES2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119546304-A | Salts of SOS1 inhibitors | 米拉蒂治疗公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119462626-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115135315-B | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-116635028-A | Modulators of c-MYC mRNA translation and their use in the treatment of cancer | 艾尼莫生物科技公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |