Sugi Predict

Sugi Predict / Compounds / SCHEMBL698709

SCHEMBL698709

SCHEMBL698709

Cc1cccc(C(=O)O)c1F

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.61
▸ ALDH1A1 P00352 3/20 0.61
▸ HPGD P15428 2/20 0.61
▸ HSD17B10 Q99714 2/20 0.61
▸ MYC P01106 1/20 0.55
▸ CYP3A4 P08684 2/20 0.52
▸ CYP2C9 P11712 2/20 0.52
▸ KMT2A Q03164 2/20 0.52
▸ KAT6A Q92794 1/20 0.51
▸ ALB P02768 1/20 0.50
▸ POLB P06746 1/20 0.50
▸ NAPRT Q6XQN6 2/20 0.49
▸ MEN1 O00255 1/20 0.49
▸ AKR1B10 O60218 1/20 0.49
▸ TRPA1 O75762 1/20 0.49
▸ ABCB11 O95342 1/20 0.49
▸ DHFR P00374 1/20 0.49
▸ LMNA P02545 1/20 0.49
▸ MPO P05164 1/20 0.49
▸ CYP1A2 P05177 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10644835 0.84 KAT6A (0.49) KDM4EALDH1A1HPGDHSD17B10MYC
SCHEMBL336107 0.84 ALDH1A1 (0.60) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL25223535 0.83 ALDH1A1 (0.45) KDM4EALDH1A1HPGDHSD17B10MYC
SCHEMBL29945818 0.83 KAT6A (0.47) KDM4EALDH1A1HPGDHSD17B10MYC
SCHEMBL1642296 0.83 KAT6A (0.47) KDM4EALDH1A1HPGDHSD17B10MYC
SCHEMBL10526573 0.83 KAT6A (0.47) KDM4EALDH1A1HPGDHSD17B10MYC
SCHEMBL879722 0.81 ALDH1A1 (0.52) KDM4EALDH1A1HPGDHSD17B10MYC
SCHEMBL6459628 0.81 KAT6A (0.46) KDM4EALDH1A1HPGDHSD17B10MYC
SCHEMBL11891100 0.80 AKR1C3 (0.52) KDM4EALDH1A1HPGDHSD17B10MYC
SCHEMBL16958399 0.80 KAT6A (0.45) KDM4EALDH1A1HPGDHSD17B10MYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516479-B1 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF CORP (US) 2016-04-20 — — EP claimed
EP-2516479-A2 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF Corporation (US) 2012-10-31 — — EP claimed
US-8211819-B2 Internal and external donor compounds for olefin polymerization catalysts BASF CORPORATION (US) 2012-07-03 — — US claimed
WO-2011084691-A2 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF CORPORATION (US) 2011-07-14 — — WO claimed
US-20110152481-A1 Internal and external donor compounds for olefin polymerization catalysts BASF CATALYSTS LLC (US) 2011-06-23 — — US claimed
CN-122070275-A Heterocyclic compound and application thereof 成都麻沸散医药科技有限公司 2026-05-19 — — CN disclosed
US-20260109699-A1 AZOLE DERIVATIVES AS SHP2 INHIBITORS IRBM S.P.A. (IT) 2026-04-23 — — US disclosed
EP-4611741-A1 TARGETING ALLOSTERIC AND ORTHOSTERIC POCKETS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-09-10 — — EP disclosed
EP-4594324-A1 AZOLE DERIVATIVES AS SHP2 INHIBITORS IRBM S.P.A. (IT) 2025-08-06 — — EP disclosed
US-12378200-B2 Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors ORSOBIO, INC. (US) 2025-08-05 — — US disclosed
CN-120129683-A Azole derivatives as SHP2 inhibitors IRBM股份公司 2025-06-10 — — CN disclosed
US-20250145572-A1 Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD) Inhibitors ORSOBIO INC (US) 2025-05-08 — — US disclosed
WO-2003068230-A1 SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE PHARMACIA CORPORATION (US) 2003-08-21 — — WO disclosed
EP-1313696-A2 AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS ABBOTT LABORATORIES (US) 2003-05-28 — — EP disclosed
CN-1096292-C Method for preparing bimetallic ruthenium/tin catalyst PHODIA CHIMIE (FR) 2002-12-18 — — CN disclosed
US-20020035137-A1 Amino (oxo) acetic acid protein tyrosine phosphatase inhibitors ABBOTT LABORATORIES 2002-03-21 — — US disclosed
WO-2002018323-A2 AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS ABBOTT LABORATORIES (US) 2002-03-07 — — WO disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 — — EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 — — WO disclosed
CN-1204271-A Method for preparing bimetallic ruthenium/tin catalyst PHODIA CHIMIE (FR) 1999-01-06 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378200-B2 Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors ALDH7A1, ACMSD, AMD1 KDM4E 1040/4885ALDH1A1 370/4885HPGD 311/4885
US-20250145572-A1 Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD) Inhibitors ACMSD, ALDH7A1, ALAD KDM4E 807/4885ALDH1A1 271/4885HPGD 395/4885
US-20260109699-A1 AZOLE DERIVATIVES AS SHP2 INHIBITORS PTPN1, PTPN5, PTPN3 KDM4E 1329/4885ALDH1A1 2460/4885HPGD 4547/4885
US-20020035137-A1 Amino (oxo) acetic acid protein tyrosine phosphatase inhibitors PPM1A, PTPRO, PTP4A1 KDM4E 2015/4885ALDH1A1 299/4885HPGD 2547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.